Download citation. Received : 04 March Accepted : 26 June Published : 13 January Issue Date : February Anyone you share the following link with will be able to read this content:. Sorry, a shareable link is not currently available for this article. Provided by the Springer Nature SharedIt content-sharing initiative.
Skip to main content. Search SpringerLink Search. Unfortunately, because of socioeconomic restraints, isolation or with other systemic symptoms. The prognosis of the patient abandoned the treatment after the induction ALL with orbital involvement is poor.
Systemic chemo- chemotherapy was completed. Radiotherapy may be omitted in patients who tions of acute leukemia. While orbital mass is commonly seen achieve complete response to chemotherapy with no residual in AML and is known as granulocytic sarcoma, it is un- orbital mass. Only two patients were diagnosed with ALL [2]. The outcomes vary from complete re- regarding the publication of this paper.
Bidar et al. To date, there is no data and wrote the manuscript. PC reviewed clinical and lab- Ophthalmic involvement could also be the manifestation oratory data and wrote the manuscript. All authors gave of relapsed ALL. Tabata et al. The patient achieved engraftment but developed a right orbital mass on day 21 after HSCT and later progressed to systemic relapse [8].
Acknowledgments Tayler et al. The ophthalmic involvement was bilateral in one patient. All three received chemotherapy and radiotherapy. Two patients achieved References complete remission but one had cataract and one had [1] J.
Ramamoorthy, R. Jain, A. Trehan, A. Saxena, and permanent visual acuity impairment [9]. Shields, C. To learn more, view our Privacy Policy. To browse Academia.
Log in with Facebook Log in with Google. Remember me on this computer. Enter the email address you signed up with and we'll email you a reset link. Need an account? Click here to sign up. Download Free PDF. Pathogenesis and prognostication in acute lymphoblastic leukemia Fprime reports, Jacob Rowe. Tsila Zuckerman. A short summary of this paper. Download Download PDF. Translate PDF.
You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. Multiparameter flow cytometry may be used to detect minimal residual disease in acute leukemia because leukemic cells often display aberrant phenotypes when compared to normal cells.
One limitation of this approach in B-precursor ALL is that leukemic phenotypes are often qualitatively similar to normal marrow B progenitors, though it has long been recognized that the latter show a predictable pattern of antigen expression with differentiation. A series of dual parameter displays were created in which normal B precursors occupied predictable regions.
Because the pattern of antigen expression in normals is very reproducible, it is possible to create a fixed set of geometrical regions to define the normal; this makes analysis of an unknown sample very straightforward. We conclude that our approach could be employed as a simple method for the detection of minimal residual disease in B-precursor ALL, and unlike many other methods should prove applicable to virtually all cases of this malignancy.
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